Welcome to the VNUHCM Journal of Health Sciences (ISSN 2734-9446) (Tạp chí Đại học Quốc gia Thành phố Hồ Chí Minh - Khoa học Sức khoẻ)

The Journal of Health Sciences is dedicated to advancing the understanding and application of knowledge in all areas related to health and healthcare. Our scope encompasses a broad range of interdisciplinary topics including, but not limited to:

Public Health: Research addressing population health, epidemiology, health promotion, disease prevention, and health policy.

Clinical Research: Studies investigating diagnosis, treatment, and management of diseases, as well as clinical trials and outcomes research.

Healthcare Management: Exploration of organizational and managerial aspects of healthcare delivery, quality improvement, healthcare economics, and healthcare systems.

Health Informatics: Innovations in health information technology, electronic health records, telemedicine, and health data analytics.

Health Education: Strategies for health education, health literacy, patient empowerment, and community-based interventions.

Global Health: Examination of health disparities, international health systems, global health governance, and cross-cultural health issues.

Mental Health and Well-being: Research focusing on mental health disorders, psychological well-being, psychotherapy, and psychiatric interventions.

Nutrition and Dietetics: Studies related to nutrition science, dietary patterns, nutritional interventions, and diet-related diseases.

Environmental Health: Investigations into environmental determinants of health, occupational health, pollution, climate change, and sustainable health practices.

Healthcare Ethics and Law: Exploration of ethical issues in healthcare delivery, patient rights, healthcare law, and bioethics.

 The Journal of Health Sciences welcomes original research articles, systematic reviews, meta-analyses, theoretical perspectives, case studies, and letters to the editor. Our aim is to provide a platform for scholarly exchange and dissemination of high-quality research that contributes to improving health outcomes and advancing the field of health sciences globally.

Latest Articles

  1. Case Reports

    A rare variant in the confluence of the inferior mesenteric vein: a report on a formalin-embalmed cadaver

    Tuyen L., Nguyen H., Duc N., Ninh N., Trinh N.
    This case provides additional descriptive evidence of the anatomical diversity of the inferior
    mesenteric vein in the Vietnamese population. Early recognition of such variants using CT angiography and three-dimensional reconstruction may help surgeons adjust their operative approach,
    reduce intraoperative complications, and improve surgical safety. However, as this is a single cadaveric case report, further studies on larger sample sizes are needed to confirm these observations.
    Published: 2025-12-31780-786
  2. Original research

    Duration of Pregnancy Prolongation with Atosiban in Twin Pregnancies Diagnosed with Threatened Preterm Labor

    Yen N., Tuan H., Nhung N., Hoa N.
    Twin pregnancy is a high-risk condition associated with numerous maternal and fetal complications. Common complications include hypertensive disorders, preterm birth, congenital abnormalities, and those specific to twin gestations. Among these, preterm birth is the most prevalent, with a rate exceeding 50% in twin pregnancies, 10.8 times higher than in singleton pregnancies. Preterm birth not only leads to significant neonatal morbidity and mortality but also imposes a substantial economic burden for neonatal care. Approximately 70% of preterm infant deaths occur in the neonatal period, and 50% of these children die within the first five years of life. The cornerstone of managing threatened preterm labor focuses on preventing or inhibiting uterine contractions, thereby prolonging pregnancy to allow for the administration of corticosteroids for fetal lung maturation, magnesium sulfate for fetal neuroprotection, and transfer to a tertiary care center. Atosiban is a highly effective tocolytic agent with minimal maternal and fetal side effects.
    Published: 2025-12-31787-794
  3. Original research

    Development and Validation of a Sensitive RP-HPLC Method for Quantifying Oxaliplatin in ZIF-8 as a Drug Delivery System

    Pham Q., Nguyen X., Pham N., Nguyen L., Le T., Doan T.
    Oxaliplatin is widely utilized in cancer therapy but is often limited by significant side effects. Zeolitic Imidazolate Framework-8 (ZIF-8), a type of metal-organic framework nanoparticle, has been investigated as a delivery system for oxaliplatin, offering advantages such as targeted cancer cell delivery and controlled drug release. This study aimed to develop and validate a sensitive, straightforward, and cost-effective reverse-phase high-performance liquid chromatography (RP-HPLC) method for quantifying oxaliplatin within ZIF-8.
    Published: 2025-12-31795-804
  4. Narrative review

    Management Strategies for Graves’ Disease in Children: Current and Future Perspectives

    Tran L., C., Nguyen P., M., Bui N., Q., Le M., H., Truong M. A. M.
    Graves’ disease is the leading cause of hyperthyroidism in children, characterized by an autoimmune process that stimulates excessive thyroid gland activity. Although less common in children than in adults, the disease can significantly impact their physical and psychological development. Currently, three primary treatment strategies for pediatric Graves’ disease include antithyroid drugs (ATDs), radioactive iodine (RAI), and thyroidectomy. Antithyroid drugs can be administered using different medications, dosages, and approaches, with methimazole considered the first-line therapy due to its relative safety and effectiveness. However, they are associated with a low remission rate and a high risk of relapse. RAI is used more cautiously in younger children due to concerns over potential long-term effects on growth and development. Meanwhile, thyroidectomy, typically performed as a total thyroidectomy, offers a definitive treatment but carries risks of complications, including damage to the recurrent laryngeal nerve or hypoparathyroidism. Future prospects focus on targeted and personalized therapies that directly address the underlying pathogenesis of the disease. Novel treatments are exploring monoclonal antibodies that specifically target molecules such as the thyroid-stimulating hormone receptor (TSHR) or associated cytokines, aiming to modulate the autoimmune response. Additionally, immune-modulating therapies that regulate B-cell activity and mitigate autoimmune reactions are under development. These potential therapeutic strategies aim not only to enhance treatment efficacy but also to minimize adverse effects, laying the foundation for improving the quality of life for children with Graves’ disease.
    Published: 2025-12-29768-779
  5. Original research

    Sarcopenia in elderly patients with knee osteoarthritis

    Han D., Ha T., Hieu H., Nam H., Hue L., Dung H., Ngoc C., Cong N.
    The presence of sarcopenia in elderly patients with knee osteoarthritis (KOA) increases the severity of knee degeneration, heightens knee pain levels, raises the risk of falls, reduces activity capacity, and decreases quality of life, thereby leading to higher rates of disability and dependency.
    Published: 2025-12-18760-767
  6. Original research

    Developing and validation of high performance liquid chromatography method for determination of carboplatin-loaded Metal-organic framework materials

    Pham Q., Do H., Nguyen T., Huong P., Nguyen L., Doan T., Le T.
    Carboplatin is widely used in cancer treatments despite several adverse effects. Metal-organic framework nanoparticles (MOF) were used to load carboplatin, which could improve selectivity to cancerous tissues and control the release profile of this compound. This study aimed to develop and validate a sensitive, simple, cost-effective RP-HPLC method for quantifying carboplatin in MOF.
    Published: 2025-12-18747-759
  7. Original research

    Prevalence of adolescent pregnancy giving birth at Delivery Department - Tu Du Hospital and associated factors

    Tran L., Nguyen T., Truong D.
    The rate of adolescent pregnancy has been on the rise in recent years, leading to adverse pregnancy outcomes for the mother and the fetus.
    Published: 2025-06-30711-718
  8. Original research

    Students’ perspectives of E-learning utilization in medical students: A qualitative study at the University of Medicine and Pharmacy at Ho Chi Minh City

    Nguyen T., Ly T., Tran T., Le L., Duong T., Tran T., Huynh Q. T. V.
    To fully harness the e-learning potential, it is crucial to address the challenges faced by students and continuously improve the platform based on their feedback. This could involve expanding access to digital resources and developing new features tailored to different educational stages and disciplines. Addressing these issues can render e-learning a robust and effective tool for enhancing educational outcomes.
    Published: 2025-06-30732-739
  9. Original research

    E-Learning in medical education at the University of Medicine and Pharmacy at Ho Chi Minh City: Perspectives from academic staffs

    Nguyen T., Ly H., T., Tran K., T., Le L., Duong T., T., Tran T., Huynh Q.
    In the post-COVID-19 era, medical education has undergone significant transformations, with a stronger emphasis on developing online learning platforms to support faculty in managing online teaching. However, the findings of this study indicate that the potential of online learning platforms for educational purposes remains underutilized, as users face various challenges during their use. A qualitative study was conducted during the 2022 – 2023 academic year. The research team conducted in-depth interviews with 11 faculty members at the University of Medicine and Pharmacy in Ho Chi Minh City (UMP). The analysis of the interview data revealed four main themes: (1) Challenges in uploading and managing materials provided to students; (2) Lack of training on the E-learning platform for faculty; (3) Limited functionalities supporting interaction between faculty and students; (4) Suggestions for optimizing the use of the E-learning platform. To fully harness the features of the E-learning platform, it is essential to address the identified issues and continuously improve the platform by incorporating training, enhancing accessibility to digital resources, and developing new features based on user feedback and needs. Addressing these challenges can make the E-learning platform a more effective tool for improving the quality of education.
    Published: 2025-06-30740-746
  10. Original research

    The study of maternal spinal anesthesia-induced hypotension during Cesarean section at Tu Du Maternal Hospital, Vietnam - the incidence and related risks

    Thuong N., Mai N., Minh C., Minh N., Vy D., Thanh L.
    Background and Aims: This study aimed to identify the incidence of spinal anesthesia (SA)-induced hypotension in those mothers who underwent cesarean section (CS) and evaluate associated factors (related to pregnant women, fetus, and operation process).
    Published: 2025-06-30719-731

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