Latest Articles

  1. Original research

    Effect of prf on pain, swelling, trismus after surgical removal of impacted lower third molars

    Phan T., Vu H., Nguyen K., Nguyen L.
    The aim of this study is to evaluate the effects of PRF on reducing pain, swelling and trismus after surgical removal of impacted lower third molars.
    Published: 2021-11-21In press
  2. Original research

    Validity and reliability of child oral health impact profile among Vietnamese children from 12 to 15 years old

    La H., Hoang H., Dien V., Ngo C.
    Child Oral Health Impact Profile (COHIP) is a tool to evaluate the impact of oral health related to quality of life. However, there is no Vietnamese standardized COHIP version in Vietnam. This study assessed the validity and reliability of the Vietnamese version of COHIP questionnaire (COHIP-VIET) among Vietnamese children from 12 to 15 years old.
    Published: 2021-11-20271-278
  3. Original research

    Application of the Beck Depression Inventory – II, Zung Self-Rating Anxiety Scale và Pittsburgh Sleep Quality Index on student of School of Medicine – Vietnam National University Ho Chi Minh City: a pilot study

    Nguyễn Ân Nguyen N., Bui M., Le M., Vo N., Hoang N., Chung N., Nguyen D.
    The study aims to applicate of the Beck Depression Inventory - II (BDI-II), Zung Self-Rating Anxiety Scale (SAS) and Pittsburgh Sleep Quality Index (PSQI) on medical students.
    Published: 2021-11-15In press
  4. Original research

    Study on collagen type 11A1 and collagen type 4A1 expression in neuroblastoma

    Luu Thi Phuong T., Bui B.
    Neuroblastoma (NB) is the most common cause of solid cancer-related high death in children. Previous research shows that tumor microenvironment that involved Collagen that plays an important as heterogeneous role in its tumor microenvironment remodeling. However, less study has been described the collagen expression in the NB. Therefore, this study aimed to elucidate the expression of two prominent collagens (COL11A1 and COL4A1) which can be express abnormally in the NB cancer cohort in Vietnam.
    Published: 2021-11-14In press
  5. Original research

    Knowledge, attitudes, practices and barriers for implementation of preventing measures toward COVID-19 among residents of Tan Phu district, Ho Chi Minh city

    Nguyễn Ân Chung N.,ã Nguyễn Dũn., Nguyễn N.,ọc Võ N.,ĩa Bùi M.
    The study aims to investigate the correct knowledge, attitudes, practices, and barriers of residents who live in Tan Phu district, HCMC, toward COVID-19 prevention, during the pandemic.
    Published: 2021-11-06247-256
  6. Original research

    The control of Low-Density Lipoprotein Cholesterol in the elderly at the clinic of health protective committee for high ranking cadre of Ca Mau province

    Vuong T., Le T., Tran H., Ho D., Nguyen C.
    Intensive control of low-density lipoprotein (LDL-C) helps the elderly to prevent primary and secondary cardiovascular events. Objective: Study on the current status of LDL-C control in the elderly at the clinic of Health Protective Committee for High Ranking Cadre of Ca Mau province from November 2020 to January 2021 according to the 2019 European Society of Cardiology and European Atherosclerosis Society guidelines (ESC/EAS 2019).
    Published: 2021-11-06257-264
  7. Narrative review

    Impact of SARS-CoV-2 on female fertility and pregnancy

    Trần Dũn., Ngô T.ỳ
    SARS-CoV-2 is a causative agent of an enormous pandemic, initiated from Wuhan, China in 2019 and then spread around the world. This virus infects not only the human respiratory tract but also other organs such as the heart, kidneys, testis, etc. by interacting with ACE2 and TMPRSS2 proteins. Until now, evidence of SARS-CoV-2 infectability in women’s reproductive tract, zygotes, embryos, and risk of vertical transmission is limited. Furthermore, some results from several studies are still incompatible. Cells of women’s reproductive system may have less susceptibility to SARS-CoV-2. However, human oocytes and embryos may be more vulnerable to SARS-CoV-2 because of the difference in co-expression of two transmembrane proteins - ACE2 and TMPRSS2, in those cells. SARS-CoV-2 increases the risk of negative impacts on different levels in different stages of pregnancy, as well as has a potential risk of vertical transmission. The recent evidence suggests that we need to pay more attention to taking care of SARS-CoV-2 infected pregnant women, especially in the first trimester of pregnancy.
    Published: 2021-11-06271-280
  8. Case Reports

    The treatment outcome of conjunctival resection for conjunctivochalasis: A case report

    Nguyễn Đa., Diep T., Duong Hươn., N., Lam V., Tran T.
    Conjunctivochalasis was defined as loose and nonedematous redundant conjunctiva located between the ocular globe and eyelids, especially at the lower fornix. These redundant conjunctival folds cause a range of symptoms, including grittiness, dryness, epiphora and blurry vision etc. due to the interior nasal punctum blockage and decreased tear film stability. Decreased tear film stability, pooling tears in the eyelid cul-de-sac, tear meniscus disruption, increasing mechanical friction, cause corneal epithelial damage and ocular surface inflammation. Conjunctivochalasis is a common ocular surface disease but well overlooked and often misdiagnosed with dry eye, meibomian gland disease or allergic conjunctivitis. The difficulty in diagnosing conjunctivochalasis is that the symptoms are non-specific, the onset is insidious and many clinicians do not recognize the significance of the conjunctival folds. Surgical treatment is indicated when refractory to medical management (artificial tears, anti-inflammation eyedrops) in order to reconstruct the conjunctival surface and tear menicus function. To better understand the efficacy of surgical management of conjunctivochalasis, we report a case of conjunctival resection before and three months after surgery.
    Published: 2021-11-06265-270
  9. Original research

    Prevalence of gestational diabetes and related factors of pregnant women having prenatal care at Tu Du hospital in 2020

    Le N., Nguyễn V., Trần Q., Lê D., Phạm H.,ếu Trần Lợi
    Determine the prevalence of gestational diabetes and related factors of pregnant women having prenatal care at Tu Du hospital in 2020.
    Published: 2021-11-06238-246
  10. Original research

    Study on improved protocol for the synthesis of propacetamol hydrocloride

    Nguyễn V., Nguyen H., Huân Lê Khánh T.,ần Lan N.,ễn Phúc N.,ô Thiện N.,ễn Nguyen B., A., Trần N.,ân Phan T.,ắn., Trần Hùn., Trí Lê
    (4-Acetamidophenyl) 2-(diethylamino) acetate hydrochloride (propacetamol) is a prodrug of pacetaminophenol (paracetamol). Propacetamol is usually administered intravenously and has a rapid analgesic effect. Moreover, propacetamol is water soluble and is used in postoperative care when the patients cannot take oral or rectal p-acetaminophenol. Studies on propacetamol synthesis on laboratory scale as well as industrial scale with safe, simple and economic procedures are crucial. Over the last few years, a number of studies have been demonstrating the advantages of replacing the traditional heating methods with microwave irradiation. The improved procedure for synthesizing (4-acetamidophenyl) 2-(diethylamino) acetate hydrochloride with N-(4- hydroxyphenyl) acetamide as the starting material is described in this study. Reaction conditions including molar ratio, solvent, catalyst and reaction time were evaluated in order to enhance the synthesis performance. The structure of products obtained after each reaction were determined by using HPLC, MS and NMR methods. The results show a simple process and short reaction time for synthesis of propacetamol from p-acetaminophenol as the starting material. Additionally, the quality and purity of final products meet pharmaceutical standards and high total reaction yield is achieved through the application of microwaves with the suitable catalysts and organic solvents.
    Published: 2021-11-06229-237

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