Latest Articles

  1. Original research

    Evaluation of meniscal injury on magnetic resonance imaging and knee arthroscopy in patient with anterior cruciate ligament tear

    Toan V., T., Nguyen D., Anh L., D., N., Hien N., V., K., Khanh Hiep V., Tu L., A., Ba P., L., N., Duong N., M., Vien N. H.
    Meniscal injuries often occur associated with anterior cruciate ligament (ACL) injury (rate 55 - 80%), failure to detect meniscal tear in patients with ACL tears will make tears become more complicated and more difficult to repair over time.
    Published: 2025-01-24654-662
  2. Original research

    Microbiological profile and antibiotic utilization patterns in nosocomial pneumonia: a cross-sectional study in the intensive care unit of Thong Nhat Hospital

    Nguyen U., Le A., Huynh T., Bui Q., Pham H.
    The objective of this survey was to investigate the microbiological characteristics and antibiotic usage patterns in the treatment of hospital-acquired pneumonia (HAP) patients in the Intensive Care Unit (ICU) setting.
    Published: 2024-12-31644-653
  3. Original research

    The relationship between risk habits, oral hygiene status, and the effectiveness of radiation-induced oral mucositis treatment

    Le T., Nguyen C., Tran H., Vo T.
    To determine whether there is a relationship between risk habits, oral hygiene status, and the effectiveness of radiation-induced oral mucositis treatment.
    Published: 2024-12-31663-669
  4. Original research

    Evaluation of internal reliability and EFA analysis of students' satisfaction on Dental education program - University of Medicine and Pharmacy at Ho Chi Minh City

    Tran T., Hoang Dao B., T., Nguyen Thi T., Q., Le Ba A. D.
    Surveying learners’ opinions is one of the crucial data channels in the accreditation and quality assurance of education and training, serving as a database to help training programs consider quality improvements. Since 2019, the University of Medicine and Pharmacy at Ho Chi Minh City has conducted surveys on the satisfaction levels of graduating students regarding the quality of training programs in all undergraduate programs. However, the survey sample has not yet been statistically evaluated for internal reliability and the grouping of survey questions. In this study, the survey results of Dental programs (Dental Surgery and Dental Prosthetics programs) were used as a representative sample for statistical analysis using Cronbach’s Alpha and Exploratory Factor Analysis (EFA). The results showed that the number of survey samples collected (115 samples) met the sampling requirements. The survey questions had high Cronbach’s Alpha coefficients (above 0.8). The EFA analysis suggested regrouping the questions into three main survey groups: Quality of the training program, Quality of the teaching staff – training organization, and Quality of student support activities. This research result will serve as a basis for improving the survey model used for all other training programs at the University of Medicine and Pharmacy at Ho Chi Minh City in the coming years.
    Published: 2024-12-31670-677
  5. Original research

    Clinical characteristics and liver cirrhosis stages in patients with untreated chronic hepatitis b at thong nhat hospital

    Hà Vũ Huy Đỗ Đỗ N.,ựt Phạm Q.,ân Nguyễn Q.,ên Trương T.,ủy Trần Tườn., Nguyễn Đức
    Objective: Assessment clinical characteristics and liver fibrosis stages in chronic hepatitis B patients without specific treatment based on the combination of two non-invasive methods: APRI score and liver elasticity ultrasound using ARFI technique Materials and method: A cross-sectional descriptive study was conducted on 242 patients diagnosed with chronic hepatitis B from January to April 2024 at the Department of Gastroenterology, Thong Nhat Hospital. Data were collected on age, gender, clinical symptoms, liver function tests, and liver elastography to assess fibrosis stages. Results: From January to April 2024, a total of 242 patients met the inclusion criteria and were enrolled in the study. The mean age was 53 ± 14.39 years, and the male-to-female ratio was 3:1. The majority of patients (58.7%) were asymptomatic. The prevalence of mild liver fibrosis (F0-F1) in the study population was 25.6%, significant fibrosis (F2) was 42.6%, advanced liver fibrosis (F3) was 14.5%, and cirrhosis (F4) was 17.3%. The prevalence of significant or severe liver fibrosis was 74.4%. Conclusions: In our study, a high proportion (74.4%) of untreated chronic hepatitis B patients had moderate or severe liver fibrosis. If we rely solely on an ALT level of twice the upper limit of normal to determine treatment, as recommended in previous guidelines, we may miss many cases of severe liver fibrosis that require treatment but have normal ALT levels. This highlights the value of non-invasive methods for assessing liver fibrosis in routine clinical practice for chronic hepatitis B patients.
    Published: 2024-12-31In press
  6. Original research

    Analysis of survey results to determine factors affecting student satisfaction with training programs at Ho Chi Minh City university of medicine and pharmacy

    Le-Ba A., D., Hoang-Dao B., T., Nguyen T., T., Q., Nguyen T., P., L., Nguyen K., C., Tran T.
    Higher education quality can be approached and measured from multiple dimensions. Various classification systems and measurement tools have been developed due to the significance, quantity, and importance of service quality dimensions depending on the cultural orientation and values of stakeholders. Students play a crucial role in the development of quality assurance and accreditation systems in education. Our previous research proposed a student satisfaction survey tool consisting of three components: Program Quality, Faculty Quality - Training Organization, and Support Services Quality. To analyze and identify significant factors affecting student satisfaction and to develop targeted solutions to enhance student satisfaction, this study statistically analyzes the survey results on final-year students’ satisfaction with the training services at University of Medicine and Pharmacy at Ho Chi Minh City. A cross-sectional study with a full-sample collection method was conducted among final-year students of the regular undergraduate program from May to July 2022. An online questionnaire was administered using Education Management Software (PMT-EMS). Data, once processed and cleaned using Excel, were analyzed with STATA software. Criteria were tested with Chi-square/df values less than 5, absolute fit indices (GFI), Turker-Lewis Index (TLI), and Comparative Fit Index (CFI) values greater than 0.9, and RMSEA model error values below 0.08. Additionally, Average Variance Extracted (AVE) and Composite Reliability (CR) were used to assess reliability and convergent validity. RMSEA, Chi-square/df, CFI, GFI, and AGFI indices were used to evaluate the model. Furthermore, NFI, RFI, and IFI (greater than 0.9) were used to test model fit and the impact of observed variables. The study found that the factor most significantly affecting student satisfaction is support services. The second most influential factor is the quality of the support staff and training organization.
    Published: 2024-12-31In press
  7. Case Reports

    Spontaneous regression of a cystic hygroma: A Case Report

    Banh V., Ho T., Trinh H., Nguyen N., Do Thi K.
    Cystic hygroma, caused by defects in the formation of the venolymphatic system, is a common condition in prenatal diagnosis with a prevalence of approximately 1:1000 to 1:6000 live births. It is often associated with adverse pregnancy outcomes. According to the Society for Maternal-Fetal Medicine, up to 90% of cases diagnosised with cystic hygroma result in fetal demise. At Department of Antenatal Care - Tu Du Hospital, we report a clinical case of live newborn with prenatal diagnosis of cystic hygroma that underwent spontaneous regression during pregnancy, with normal genetic testing resul. At 5 days old, the newborn had normal echocardiography and general examination at the Children’s Hospital 2 revealed no abnomolities. Therefore, cystic hygroma is not an indication for medical termination of pregnancy. The fetus diagnosed with cystic hygroma requires appropriate prenatal counseling, genetic testing to rule out chromosomal abnormalities, and subsequent fetal ultrasound to assess the progression of cystic hygroma and exclude other fetal malformations.
    Published: 2024-12-31In press
  8. Original research

    Drug-related problems on antibiotic therapy among patients in the intensive care unit at a Grade 1 Hospital, Ho Chi Minh City

    Nguyen U., Nguyen N., Pham H., Bui Q.
    To determine prevalence, characteristics, and factors related to drug-related problems (DRPs) of antibiotic therapy among patients in the intensive care unit at a grade 1 hospital, Ho Chi Minh City.
    Published: 2024-12-31In press
  9. Narrative review

    Overview of Dravet syndrome and an update in therapeutics

    Do H.
    Dravet syndrome is a developmental epileptic encephalopathy characterized by early onset drug-resistant seizures and other clinical features, including intellectual disability and impairments in behavior, motor, and sleep which cause poor quality of life and impact the long-term course. The pathogenesis of Dravet syndrome is strongly connected to the dysfunction of the voltage-gated sodium channel, more specifically, to mutations in SCN1A gene. Epilepsy in Dravet syndrome is very refractory and seizures remain poorly controlled even with multiple conventional anti-epileptic drugs. Therapeutic approaches in Dravet syndrome have undergone tremendous changes in the lastest years and the current consensus of seizure management strategy in Dravet syndrome consists of a combination of conventional drugs and three recently approved drugs including stiripentol, cannabidiol, and fenfluramine. This review article aims to update recent changes to the therapeutic landscape for Dravet syndrome by summarizing the most key data from the clinical development of stiripentol, cannabidiol, and fenfluramine. This article also reviews and discusses the latest findings of other pharmacotherapies in development, including serotonergic agents, soticlestat, verapamil as well well strategies to treat the underlying cause of Dravet syndrome, including gene therapy and antisense oligonucleotides.
    Published: 2024-06-30633-643
  10. Original research

    The characteristics of clinical, microbiological and antibiotic resistance profile in patients with bacterial keratitis at Ho Chi Minh City Eye Hospital in 2020

    Tran B., Lê H., Phan A., Pham H., Nguyen L., Tran P., Pham H.
    Purpose: To investigate the epidemiological, clinical, microbiological characteristics and antibiotic resistance profile in patients with bacterial corneal ulcers at Ho Chi Minh City Eye Hospital in 2020. Methods: An observational retrospective study was conducted on 242 cases diagnosed with bacterial corneal ulcers examined at Ho Chi Minh City Eye Hospital from January 2020 to December 2020. Information about patients’ medical history, clinical symptoms, and test results was collected from medical records. Results: Bacterial keratitis was more often seen in males and in middle-age group. Injury as a risk factor accounted for a considerable proportion of cases (24,4%). Self-treatment was common (23,1%). The culture results were mainly Gram-positive (56,6%), in which coagulase-negative staphylococci (49,2%) predominates. Pseudomonas aeruginosa (26,9%) was the most common Gram-negative pathogen. The resistance rate of coagulase-negative staphylococci to common antibiotics, including fluoroquinolones group, was relatively high (50,0 – 100,0%). Meanwhile, P.aeruginosa was sensitive to many fluoroquinolones, as well as to tobramycin and ceftazidime. Notably, we recorded twelve cases of resistance to all tested antibiotics. The rate of visual acuity improvement at the time of discharge was still unfavorably low (5,8%). There were 43,0% of patients experiencing at least one serious complication: increased intraocular pressure, endophthalmitis, impending perforation and perforation of the cornea. Up to 11,6% of patients had to resort to enucleation. Conclusions: Corneal ulceration related to trauma accounted for a significant percentage. Self-medication was still common. The high rate of antibiotic resistance along with the appearance of numerous multi-drug resistance cases is very worrying. Severe consequences were left upon patients’ eyesight.
    Published: 2024-06-30624-632

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