Latest Articles

  1. Original research

    Preparation of rutin loaded niosome by ethanol injection method

    Nguyen-Truong T., Le Q., Tran T.
    Rutin has low bioavailability due to its high molecular weight and low solubility. Rutin loaded niosome is a promising solution but according to our knowledge, there is no publication about this study in both internal and international journal. This study is aim to formulate rutin loaded niosome with appropriate parameters. Rutin loaded niosome was prepared by ethanol injection method. Briefly, 45 experiments were carried out by varying the cholesterol:span 20 ratio (mol:mol), mixing temperature (40-50-60 oC), mixing time (30-40-50 minutes). These formulations were characterized in term of morphology (observation by optical microscope) and drug loading efficiency. Microscope images were used to exclude the formulations without niosome. The niosome formulations were than characterized their encapsulation efficiency by UV-Vis method. In this research, niosome was created in 7 formulations having encapsulation efficiency from 5.5% to 15.7%. The selected formulation was prepared with cholesterol:span 20 ratio of 3:7 with the formulation parameters of 40 minutes mixing time and 50 oC mixing temperature.
    Published: 2021-12-31330-337
  2. Original research

    Study on collagen type 11A1 and collagen type 4A1 expression in neuroblastoma

    Luu Thi Phuong T., Bui B.
    Neuroblastoma (NB) is the most common cause of solid cancer-related high death in children. Previous research shows that tumor microenvironment that involved Collagen that plays an important as heterogeneous role in its tumor microenvironment remodeling. However, less study has been described the collagen expression in the NB. Therefore, this study aimed to elucidate the expression of two prominent collagens (COL11A1 and COL4A1) which can be express abnormally in the NB cancer cohort in Vietnam.
    Published: 2021-12-26289-297
  3. Original research

    Application of the Beck Depression Inventory – II, Zung Self-Rating Anxiety Scale và Pittsburgh Sleep Quality Index on student of School of Medicine – Vietnam National University Ho Chi Minh City: a pilot study

    Nguyễn Ân Nguyen N., Bui M., Le M., Vo N., Hoang N., Chung N., Nguyen D.
    The study aims to applicate of the Beck Depression Inventory - II (BDI-II), Zung Self-Rating Anxiety Scale (SAS) and Pittsburgh Sleep Quality Index (PSQI) on medical students.
    Published: 2021-12-26323-329
  4. Original research

    Effect of prf on pain, swelling, trismus after surgical removal of impacted lower third molars

    Phan T., Vu H., Nguyen K., Nguyen L.
    The aim of this study is to evaluate the effects of PRF on reducing pain, swelling and trismus after surgical removal of impacted lower third molars.
    Published: 2021-12-26314-322
  5. Case Reports

    Pregnancy outcome in patients with prolonged deceleration in intrapartum fetal heart rate monitoring: A case series report

    Nguyễn N., Nguyễn H., Lê T.
    Diagnostic criteria for intrapartum fetal distress are still inconsistent. Currently, widely used tool in clinical practice is intrapartum fetal heart rate (FHR) monitoring in labor because of its convenience, non-invasiveness. Intrapartum. In contrast, the presence of prolonged deceleration in intrapartum FHR monitoring has a high predictive value of fetal distress compared with the absence of a deceleration. To evaluate the significance of prolonged deceleration intrapartum, it is necessary to combine the clinical context with features of fetal heart rate monitoring, that forms reasons and outcomes of prolonged deceleration – a “dangerous” type of deceleration in labor.
    Published: 2021-12-26298-306
  6. Original research

    Outcomes of ovarian cystectomy on pregnant patients at Tu Du hospital

    Cao H., Ngoc T., Quang L., Thanh P.
    This study aimed to evaluate the safety and adverse pregnancy outcomes during and after laparoscopy versus laparotomy for the treatment of ovarian cysts during pregnancy at Tu Du hospital from January 2015 to January 2021.
    Published: 2021-12-26307-313
  7. Original research

    Validity and reliability of child oral health impact profile among Vietnamese children from 12 to 15 years old

    La H., Hoang H., Dien V., Ngo C.
    Child Oral Health Impact Profile (COHIP) is a tool to evaluate the impact of oral health related to quality of life. However, there is no Vietnamese standardized COHIP version in Vietnam. This study assessed the validity and reliability of the Vietnamese version of COHIP questionnaire (COHIP-VIET) among Vietnamese children from 12 to 15 years old.
    Published: 2021-11-20281-288
  8. Original research

    Knowledge, attitudes, practices and barriers for implementation of preventing measures toward COVID-19 among residents of Tan Phu district, Ho Chi Minh city

    Nguyễn Ân Chung N.,ã Nguyễn Dũn., Nguyễn N.,ọc Võ N.,ĩa Bùi M.
    The study aims to investigate the correct knowledge, attitudes, practices, and barriers of residents who live in Tan Phu district, HCMC, toward COVID-19 prevention, during the pandemic.
    Published: 2021-11-06247-256
  9. Original research

    The control of Low-Density Lipoprotein Cholesterol in the elderly at the clinic of health protective committee for high ranking cadre of Ca Mau province

    Vuong T., Le T., Tran H., Ho D., Nguyen C.
    Intensive control of low-density lipoprotein (LDL-C) helps the elderly to prevent primary and secondary cardiovascular events. Objective: Study on the current status of LDL-C control in the elderly at the clinic of Health Protective Committee for High Ranking Cadre of Ca Mau province from November 2020 to January 2021 according to the 2019 European Society of Cardiology and European Atherosclerosis Society guidelines (ESC/EAS 2019).
    Published: 2021-11-06257-264
  10. Narrative review

    Impact of SARS-CoV-2 on female fertility and pregnancy

    Trần Dũn., Ngô T.ỳ
    SARS-CoV-2 is a causative agent of an enormous pandemic, initiated from Wuhan, China in 2019 and then spread around the world. This virus infects not only the human respiratory tract but also other organs such as the heart, kidneys, testis, etc. by interacting with ACE2 and TMPRSS2 proteins. Until now, evidence of SARS-CoV-2 infectability in women’s reproductive tract, zygotes, embryos, and risk of vertical transmission is limited. Furthermore, some results from several studies are still incompatible. Cells of women’s reproductive system may have less susceptibility to SARS-CoV-2. However, human oocytes and embryos may be more vulnerable to SARS-CoV-2 because of the difference in co-expression of two transmembrane proteins - ACE2 and TMPRSS2, in those cells. SARS-CoV-2 increases the risk of negative impacts on different levels in different stages of pregnancy, as well as has a potential risk of vertical transmission. The recent evidence suggests that we need to pay more attention to taking care of SARS-CoV-2 infected pregnant women, especially in the first trimester of pregnancy.
    Published: 2021-11-06271-280

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